There are some of the factors that can cause uterine fibroids to develop, such as:

• Genetic changes. Many fibroids contain changes in genes that differ from those in typical uterine muscle cells.
• Hormones. Estrogen and progesterone, two hormones that stimulate development of the uterine lining during each menstrual cycle in preparation for pregnancy, appear to promote the growth of fibroids.
• Other growth factors. Substances that help the body maintain tissues, such as insulin-like growth factor, may affect fibroid growth.
• Extracellular matrix (ECM). ECM is the material that makes cells stick together, like mortar between bricks.

There are several risk factors that can play a role in developing fibroids.These can include:

• Race:Although all women of reproductive age could develop fibroids, black women are more likely to have fibroids than are women of other racial groups. In addition, black women have fibroids at younger ages, and they're also likely to have more or larger fibroids, along with more-severe symptoms.
• Heredity:If your mother or sister had fibroids, you're at increased risk of developing them.
• Other factors:Starting your period at an early age; obesity; a vitamin D deficiency; having a diet higher in red meat and lower in green vegetables, fruit and dairy; and drinking alcohol, including beer, appear to increase your risk of developing fibroids

There are no exact prevention factors of uterine fibroids but according to our doctors experience you can prevent by using following:

• Although researchers continue to study the causes of fibroid tumors, little scientific evidence is available on how to prevent them.
• Preventing uterine fibroids may not be possible, but only a small percentage of these tumors require treatment.
• But, by making healthy lifestyle choices, such as maintaining a healthy weight and eating fruits and vegetables, you may be able to decrease your fibroid risk.